Site-Directed Mutagenesis by Engineered Zinc Finger Nucleases Ace myhomework myhomework writers acemywork

A zinc finger refers to a secondary structural motif of certain proteins. A zinc finger folds in a manner that allows it to coordinate a zinc metal. There are several zinc finger motifs; the most common is the Cys2His2 zinc finger that consists of an antiparallel ?-sheet and a ?-helix coordinated by 2 His and 2 Cys residues that bind a zinc atom.